As part of France’s Second National Endocrine Disruptor Strategy (SNPE 2), ANSES (The French Agency for Food, Environmental and Occupational Health & Safety) published on April 15, 2021, a list of 906 substances of interest because of their potential endocrine action, associated with a prioritization strategy and a method to classify them as a proven, supposed or suspected endocrine disruptor.

France is the first country to have had a National Endocrine Disruptor Strategy aiming to reduce exposure of the population and the environment to endocrine disruptors. 

Assessing their health effects is therefore a scientific challenge and an important public health issue. ANSES is one of the major players in this area. It carries out important assessment work to identify endocrine-disrupting substances.



How has this list of 906 substances of interest been established by ANSES?

ANSES compared the existing international lists of substances and the methods used, in order to compile a rigorous list of the substances of interest for which the data available are sufficient to consider an assessment based on the three points set out by the WHO (World Health Organization).

According to the WHO definition, a substance is recognised as an endocrine disruptor if it meets the three conditions below: 

  • adverse effects on health
  • altering one or more of the functions of the endocrine system
  • a biologically plausible link between these two findings 

The list of 906 substances of interest is available here:

In order to evaluate the impact on the perfumery sector, IFRA (International Fragrance Association) compared the list from ANSES (906 substances) with the IFRA Transparency List, which identifies all the ingredients used in perfumery. It results in 105 common substances between both lists.



ANSES is putting forward a methodology to establish an operational categorisation of endocrine disruptors:

ANSES underlines the need to be able to make a distinction between “known,” “presumed” and “suspected” endocrine disruptors, following an assessment.

The categories defined by ANSES would be based on the probability of a substance being an endocrine disruptor: 

  • Known: substances that are highly probable endocrine disruptors (probability of over 90%)
  • Presumed: substances that are strongly suspected of being endocrine disruptors, but with no certainty (probability of between 66% and 90%) 
  • Suspected: substances for which information received is concerning but not sufficient for clear judgement (probability of between 5% and 66%)

By providing a graduated result, this methodology should make it possible to vary the applicable rules in accordance with the uses and population groups exposed.

Last but not least, discussions are under way to create a hazard class for endocrine disruptors as part of the European CLP Regulation (Classification, Labelling and Packaging of Substances and Mixtures).



If you want further information about the scientific projects/studies on endocrine disruptors currently in progress all around the world, please reach out to us via email: or through your designated Sales Representative. 

SOZIO has launched its Biodegradable Fragrances Tool to assist with the creation of more sustainable products !

Reports suggest that the majority of global consumers would definitely change their consumption habits to reduce impact on the environment. Most of them also want to make a difference by purchasing environmentally-friendly products.

Therefore, in addition to its CLEAN fragrances collection, Sozio wanted to reinforce its dedication to sustainability by developing a new tool assessing the biodegradability of its fragrances.


What is the definition of biodegradability for a single substance ?

Biodegradability is the process by which carbon based substances are broken down by living organisms, ultimately to inorganic end products (like e.g. water or carbon dioxide) and biomass. It can proceed in the presence (aerobic biodegradability) or absence (anaerobic biodegradability) of oxygen. Biodegradability tests are made by laboratories according to internationally accepted OECD, ISO and OPPTS guidelines.

The criteria for biodegradability that are accepted by some of the eco-label groups and for other types of biodegradable substances (e.g. detergents in the EU) are the ones passing the criteria for “ready” or “inherent biodegradability” (i.e. 60-70% biodegradability in the OECD 301 series, OECD 310 or OECD 302 series).


How to determine biodegradability of fragrance mixtures ?

This is important to note that standard biodegradability tests have been developed for single substances. Biodegradability testing of mixtures is very difficult from a technical perspective. Indeed, different water solubilities and vapor pressures may provide false results.

According to the IFRA Guidance to « Green » Fragrance terminology, the testing of fragrance mixtures for biodegradability should not be an option because they are not reliable. Instead, the biodegradability of a fragrance mixture may be assessed based on data on the individual ingredients and by summing the percentages (by weight) of ingredients which are biodegradable according to, but not limited to, appropriate OECD tests.


The method described in the IFRA guidance to « Green » Fragrance terminology, is the method used by Sozio in order to develop its biodegradability tool. If you want further information about this new tool, please reach out to us via email: or through your designated Sales Representative.


Please do not hesitate to follow us on LinkedIn and our website to be informed about the last news. Our perfumers are currently working on a new collection of fragrances 100% made with biodegradable ingredients ! It will be released very soon ! Keep in touch !



PHOENIX FRAGRANCES LTD, Based In Wellingborough, United Kingdom, Has Joined SOZIO To Reinforce Its Perfumery Activities


Sozio, a French family- owned company specialized in the creation and production of fragrances compositions, continues to pursue its growth by announcing its merger with Phoenix Fragrances.


Company reinforcement


Through the sharing of resources and a common focus on their markets, Sozio will strengthen its natural fragrance expertise and will reinforce its presence on the UK market.


Phoenix Fragrances Ltd.’s business is very complementary to Sozio and will reinforce Sozio’s position in the fragrance industry and allow Phoenix to boost its development efforts.


Frederic Braud, General Manager of Sozio, said that « Phoenix Fragrances integration fits in perfectly with our strategic plan and confirms our determination to accelerate our growth on the UK market.  We will also expand our activities in the natural perfumery market and reduce our costs through various synergies in purchasing and IT activities.  We will boost investment in Phoenix’s R&D laboratories and Production site to help the company to sustain its growth.

Meanwhile, due to the great awareness of Phoenix Fragrances in the UK market, we will keep the brand separate from Sozio.

We are delighted to welcome Phoenix employees into the Sozio family as we are convinced that their enthusiasm and professionalism will contribute to our common future success. »


Tony Dalimore and Alan Parry, owners of Phoenix Fragrances, added « Based on its continuous growth, we felt the need to seek the support of a larger enterprise.   It was clear from the very first meetings that there was a high degree of mutual empathy, understanding built around similar philosophies and a dedication to moving the respective business forward »


Tony and Alan will continue to lead the Management of Phoenix Fragrances, with input and assistance of the Management team from Proxis Group and Sozio, as well as the operational teams from France.


As a result of various investments in its laboratories and factories in France : Seillans (Var), Levallois and Noyant (Maine et Loire), Piscataway (New-Jersey -USA), Hong Kong, Indonesia and very soon Dubai, Sozio is now positioned as a key global player, yet still responsive on a human scale, offering an alternative to the « heavyweights » in the fragrance industry.


About Phoenix Fragrances Limited:

Strong management team and commited employees: A family company founded in 1987 by Tony Dallimore and Alan Parry, Phoenix has a motivated and experienced staff and an innovative and customer-focused mindset.  Phoenix boasts sales of around £8M in 2020 with a 15% increase over the previous year.

Strategic location : Phoenix operates from a central location in Wellingborough with excellent logistic connections and efficient premises in the UK.

Natural fragrances : Its expertise and credibility with fragrances based on natural ingredients provide Phoenix with an important competitive advantage.

Broad range of expertise : Phoenix develops and manufactures fragrances compositions for mostly personal care and home fragrance applications but has also expertise in fine and household application.

Agile and Creative : Phoenix’s entrepreneurial and creative approach has been instrumental in generating business with rapidly growing Indie brands as well as large retailers in the UK.

International expansion : While 85% of Phoenix sales are directly or indirectly generated in the UK, it is also expanding in several markets in Europe and overseas.


About Sozio

260 years of history : Since its start in Grasse (France) in 1758, Sozio under the umbrella of Proxis Development Group, continues its international growth and reinforces its position as a leader in the field of perfumed compositions, with sales of over Euro 50 M in 2020 with a 9% increase over the previous year.

A family owned company : Driven by craftmanship, independance and its entrepreneurial spirit, all of our employees share the same family values.

A Global   R&D presence : With 4 creative perfumery centers in Seillans (Var- France) in the region of Grasse specialised in Fine fragrances, Levallois- France specialised in conventional fragrances, Piscataway -NJ (USA), Hong Kong, Jakarta (Indonesia) and soon Dubai (UEA) and a team of very experienced perfumers, evaluators, innovation managers, laboratory assistants and regulatory managers. All of our R&D centers are working on the same creation software and all of our sites are equiped with olfactive booths, GCMS, compounding robots and state of the art lab equipment.

We also provide fragrances in multiple forms, such as microencapsulation, scented gels, RTU Reed Diffusers, etc…

A worldwide manufacturing presence : We serve our clients from 4 factories located in Noyant (West of France), Piscataway (New Jersey-USA), Hong Kong and Jakarta (Indonesia) with semi-automatized production tools to be closer to our customers.

A large international sales presence : We support our customers with 10 representative offices in France, Spain, Germany, Italy, Israel, Dubai, Canada, USA, Vietnam, Hong Kong, Philippines and Indonesia and selected dedicated agents and distributors in the countries where we don’t have a direct presence.

A strong Marketing and Communication team : Sozio offers regular development of market studies and creative concepts as well as our presence in the main Trade shows around the world (In-Cosmetics Europe and Asia, Beautyworld in Dubai, SCC, ISSA and NCA in the USA) and internal perfumery seminars to our customers.

A Global Expertise in Natural and Clean fragrances : As our perfumers have a long experience of using a natural perfumery pallette with the enrichment of natural isolates as well as the safest raw ingredients to answer the development of the « Clean Beauty » through our CLEAN FRAGRANCES.

We also very recently launched our range of pure and natural essential oils « Botanicals by Sozio », sourced directly from local producers, that we are bringing now to our customers.

Corporate Social Responsability : Sozio offers an ambitious program, including an ethical way of conducting business, a social code of conducts with all of our employees worldwide and a strong commitment to our Environnement responsability.

Multiple international certifications :  All of our main facilities are ISO 9001 and Ecovadis certified, our facilities in France and USA are also Organic certified (through Ecocert or NOP-USDA), and our facilities in Hong Kong and Indonesia  are also Halal certified.