Sozio, a French family-owned company specialized in the creation and production of fragrances compositions, continue its growth by announcing its acquisition of Synarome.

Through a vertical integration from the ingredients to the fragrance creation and manufacturing, Sozio will strengthen its position in the field of organic synthesis, perfumery specialties  and distillation for the fragrance industry.
Frédéric Braud, General Manager of Sozio, said that : « Besides the iconic ingredients which have made the reputation of Synarome such as Ambrarome or Animalis, Synarome produces more than 200 aromachemicals and specialties for the global F&F industry. Sozio ambition is to come-back to its historical roots, the creation and manufacturing of natural perfumery ingredients which have been at the heart of the company for more than 200 years ».

Achille Riviello, General Manager of Synarome, added : « Due to our growth , we felt we need the support of a larger enterprise, able to increase our investments in our R&D center and production facility and sharing the same vision on the future of perfumery ».
As a result of its latest investments in the UK with the acquisition of Phoenix fragrances, in Asia with the creation of its new factory in Jakarta during the first quarter 2021, a new factory planned in China in 2022 and in Middle East with the building of a laboratory this summer in Dubai, Sozio is emerging as a key global player.

Yet still responsive, on a human scale, offering an alternative to the « heavyweights » of the fragrance industry.


As part of France’s Second National Endocrine Disruptor Strategy (SNPE 2), ANSES (The French Agency for Food, Environmental and Occupational Health & Safety) published on April 15, 2021, a list of 906 substances of interest because of their potential endocrine action, associated with a prioritization strategy and a method to classify them as a proven, supposed or suspected endocrine disruptor.

France is the first country to have had a National Endocrine Disruptor Strategy aiming to reduce exposure of the population and the environment to endocrine disruptors. 

Assessing their health effects is therefore a scientific challenge and an important public health issue. ANSES is one of the major players in this area. It carries out important assessment work to identify endocrine-disrupting substances.



How has this list of 906 substances of interest been established by ANSES?

ANSES compared the existing international lists of substances and the methods used, in order to compile a rigorous list of the substances of interest for which the data available are sufficient to consider an assessment based on the three points set out by the WHO (World Health Organization).

According to the WHO definition, a substance is recognised as an endocrine disruptor if it meets the three conditions below: 

  • adverse effects on health
  • altering one or more of the functions of the endocrine system
  • a biologically plausible link between these two findings 

The list of 906 substances of interest is available here:

In order to evaluate the impact on the perfumery sector, IFRA (International Fragrance Association) compared the list from ANSES (906 substances) with the IFRA Transparency List, which identifies all the ingredients used in perfumery. It results in 105 common substances between both lists.



ANSES is putting forward a methodology to establish an operational categorisation of endocrine disruptors:

ANSES underlines the need to be able to make a distinction between “known,” “presumed” and “suspected” endocrine disruptors, following an assessment.

The categories defined by ANSES would be based on the probability of a substance being an endocrine disruptor: 

  • Known: substances that are highly probable endocrine disruptors (probability of over 90%)
  • Presumed: substances that are strongly suspected of being endocrine disruptors, but with no certainty (probability of between 66% and 90%) 
  • Suspected: substances for which information received is concerning but not sufficient for clear judgement (probability of between 5% and 66%)

By providing a graduated result, this methodology should make it possible to vary the applicable rules in accordance with the uses and population groups exposed.

Last but not least, discussions are under way to create a hazard class for endocrine disruptors as part of the European CLP Regulation (Classification, Labelling and Packaging of Substances and Mixtures).



If you want further information about the scientific projects/studies on endocrine disruptors currently in progress all around the world, please reach out to us via email: or through your designated Sales Representative. 

SOZIO has launched its Biodegradable Fragrances Tool to assist with the creation of more sustainable products !

Reports suggest that the majority of global consumers would definitely change their consumption habits to reduce impact on the environment. Most of them also want to make a difference by purchasing environmentally-friendly products.

Therefore, in addition to its CLEAN fragrances collection, Sozio wanted to reinforce its dedication to sustainability by developing a new tool assessing the biodegradability of its fragrances.


What is the definition of biodegradability for a single substance ?

Biodegradability is the process by which carbon based substances are broken down by living organisms, ultimately to inorganic end products (like e.g. water or carbon dioxide) and biomass. It can proceed in the presence (aerobic biodegradability) or absence (anaerobic biodegradability) of oxygen. Biodegradability tests are made by laboratories according to internationally accepted OECD, ISO and OPPTS guidelines.

The criteria for biodegradability that are accepted by some of the eco-label groups and for other types of biodegradable substances (e.g. detergents in the EU) are the ones passing the criteria for “ready” or “inherent biodegradability” (i.e. 60-70% biodegradability in the OECD 301 series, OECD 310 or OECD 302 series).


How to determine biodegradability of fragrance mixtures ?

This is important to note that standard biodegradability tests have been developed for single substances. Biodegradability testing of mixtures is very difficult from a technical perspective. Indeed, different water solubilities and vapor pressures may provide false results.

According to the IFRA Guidance to « Green » Fragrance terminology, the testing of fragrance mixtures for biodegradability should not be an option because they are not reliable. Instead, the biodegradability of a fragrance mixture may be assessed based on data on the individual ingredients and by summing the percentages (by weight) of ingredients which are biodegradable according to, but not limited to, appropriate OECD tests.


The method described in the IFRA guidance to « Green » Fragrance terminology, is the method used by Sozio in order to develop its biodegradability tool. If you want further information about this new tool, please reach out to us via email: or through your designated Sales Representative.


Please do not hesitate to follow us on LinkedIn and our website to be informed about the last news. Our perfumers are currently working on a new collection of fragrances 100% made with biodegradable ingredients ! It will be released very soon ! Keep in touch !